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Tribromoethyl alcohol

Name: Tribromoethyl alcohol
Brand: TargetMol
SKU: T0807
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0807Cas No. 75-80-9

Alias Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-Tribromoethanol

Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.
This product also provides a ready to use version without the need for preparation, with better stability and repeatability. Ready To Use Tribromoethanol: C0183 1.25% Avertin (Anesthesia For Mice) and C0184 2.5% Avertin (Anesthesia For Rat).

Tribromoethyl alcohol

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Purity: 99.98%

Catalog No. T0807Alias Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-TribromoethanolCas No. 75-80-9

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$30	-	In Stock
5 g	$61	-	In Stock
1 mL x 10 mM (in DMSO)	$30	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA GC HNMR HPLC

Product Introduction

Bioactivity

Description	Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice. This product also provides a ready to use version without the need for preparation, with better stability and repeatability. Ready To Use Tribromoethanol: C0183 1.25% Avertin (Anesthesia For Mice) and C0184 2.5% Avertin (Anesthesia For Rat).
In vivo	Tribromoethanol has been proposed as an acceptable anaesthetic in dogs, cats, mice, rats, and gerbils. It possesses a concentration dependent irritant effect. When used at low concentration, it displays good anesthetic effect. A high dose of tribromoethanol is not a suitable anesthetic for major surgery in all mouse strains because of the risk of pathologic changes in the abdominal organs, such as retention of the digestive tract, peritonitis, and fibrinoid adhesion[1][2].
Synonyms	Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-Tribromoethanol

Chemical Properties

Molecular Weight	282.76
Formula	C₂H₃Br₃O
Cas No.	75-80-9
Smiles	C(CO)(Br)(Br)Br
Relative Density.	2.866 g/cm3

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 237 mg/mL (838.17 mM), Sonication is recommended.

H2O: 40 mg/mL (141.46 mM), Sonication is recommended.

Ethanol: 52 mg/mL (183.9 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (17.68 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5366 mL	17.6828 mL	35.3657 mL	176.8284 mL
5 mM	0.7073 mL	3.5366 mL	7.0731 mL	35.3657 mL
10 mM	0.3537 mL	1.7683 mL	3.5366 mL	17.6828 mL
20 mM	0.1768 mL	0.8841 mL	1.7683 mL	8.8414 mL
50 mM	0.0707 mL	0.3537 mL	0.7073 mL	3.5366 mL
100 mM	0.0354 mL	0.1768 mL	0.3537 mL	1.7683 mL

Calculator

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Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc