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Tribromoethyl alcohol

Name: Tribromoethyl alcohol
Brand: TargetMol
SKU: T0807
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0807Cas No. 75-80-9

Alias Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-Tribromoethanol

Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.

Tribromoethyl alcohol

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Purity: 99.98%

Catalog No. T0807Alias Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-TribromoethanolCas No. 75-80-9

Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.

Pack Size	Price	Availability
1 g	$30	In Stock
5 g	$61	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Purity:99.98%

Resource Download

COA GC HNMR HPLC

Product Introduction

Bioactivity

Description	Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.
In vivo	Tribromoethanol has been proposed as an acceptable anaesthetic in dogs, cats, mice, rats, and gerbils. It possesses a concentration dependent irritant effect. When used at low concentration, it displays good anesthetic effect. A high dose of tribromoethanol is not a suitable anesthetic for major surgery in all mouse strains because of the risk of pathologic changes in the abdominal organs, such as retention of the digestive tract, peritonitis, and fibrinoid adhesion[1][2].
Synonyms	Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-Tribromoethanol

Chemical Properties

Molecular Weight	282.76
Formula	C₂H₃Br₃O
Cas No.	75-80-9
Smiles	C(CO)(Br)(Br)Br
Relative Density.	2.866 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 237 mg/mL (838.17 mM), Sonication is recommended.

H2O: 40 mg/mL (141.46 mM), Sonication is recommended.

Ethanol: 52 mg/mL (183.9 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (17.68 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5366 mL	17.6828 mL	35.3657 mL	176.8284 mL
5 mM	0.7073 mL	3.5366 mL	7.0731 mL	35.3657 mL
10 mM	0.3537 mL	1.7683 mL	3.5366 mL	17.6828 mL
20 mM	0.1768 mL	0.8841 mL	1.7683 mL	8.8414 mL
50 mM	0.0707 mL	0.3537 mL	0.7073 mL	3.5366 mL
100 mM	0.0354 mL	0.1768 mL	0.3537 mL	1.7683 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc